Target Journal List (IF: Version 2025)
Journal of Hematology & Oncology (IF: 40.4)
Cancer Communications (IF: 24.9)
Nature Communications (IF: 15.7)
Trends in Biotechnology (IF: 14.9)
Nucleic Acids Research (IF: 13.1)
Journal of Advanced Research (IF: 13.0)
Experimental and Molecular Medicine (IF: 12.9)
International Journal of Oral Science (IF: 12.2)
Materials Today Bio (IF: 10.2)
Nature Structural & Molecular Biology (IF: 10.1)
Briefings in Bioinformatics (IF: 7.7)
Molecular Systems Biology (IF: 7.7)
British Journal of Cancer (IF: 6.8)
Journal of Bone and Mineral Research (IF: 5.9)
Research Topics
Aging (Bone, Brain, Immune)
Various Cancers (Lung, Head&Neck, Gastric, Colon, Brain, Metastasis, Neoantigen)
Basic Molecular Biology (Differentiation, Proliferation)
Basic Dental Medicine
Complex Disease (OPLL, COPD, MDD)
Neuroscience (Alzheimer's, MDD)
Bioinformatics (Pipelines, Biostatistics, ML & AI, Algorithm)
All-NGS (DNA, Bulk & scRNA-seq, Spatial Tx, Epigenome, Proteomics, TCR/BCR, Microbiome)
High Impact Journal
Under Review
Ongoing Project
Patent
Conference
* Co-first · # Corresponding
Spatial transcriptomic atlas of primary gastric cancer using Visium HD and tissue microarrays
Mapping the cellular interactome in gastric cancer: Integrated analysis of primary tumors and ascites organoids uncovers immune evasion mechanisms
Integrative single-cell and spatial transcriptomics reveal the regulatory landscape of Runx2 in cranial suture morphogenesis and CCD-like skeletal phenotypes
Deciphering 3D Chromatin Architecture via Spatial Density-Based Analysis of Hi-C Data
4DN chromatin structure in differentiation of osteoblast precursor cell line derived from Mus musculus calvaria
Spatial Transcriptomic analysis of Aging and Alzheimer's Disease Using the Pin1 KO Model
Single-Cell Transcriptome Analysis of Pure and Mixed-Type Lung Adenocarcinomas: Unraveling Molecular Insights
Current Trends and Future Perspectives in All-Solid-State Battery (ASSB): A Strategic Analysis
Analysis of Ovary metastasis gastric cancer with VisiumHD and Xenium
Comprehensive Clinical-Genomic Profiling of PD-1/PD-L1 Pathway Alterations in Cancer
Clonal selection during organoid culture drives genomic divergence in gastric cancer patient-derived organoids
Spatial Profiling of SP142 Discordance Identifies TAP-Mediated Immune Ignorance and Primary Resistance to Immunotherapy in PD-L1-Positive Gastric Cancer
Immune-Responsive Bioinks Enable Intelligent Vision-Guided In situ Robotic Bioprinting to Accelerate Diabetic Wound Healing via Macrophage Immunomodulation
The global patent landscape of Adeno-associated virus-based gene therapeutics
Nucleome dynamics and histone priming by pioneer transcription factors drive osteoblast differentiation
The spatial transcriptomic landscape of 3D vascularized iPSC-derived muscle tissue in volumetric muscle loss murine model
ROS-Induced Downregulation of LncRNA H19 Impairs Osteogenic Differentiation Without Triggering Senescence
A spatiotemporal molecular portrait of gastric neuroendocrine tumor grade 3 reveals tumor plasticity and niche adaptation
Immature Neutrophil Accumulation causes the Decreased Osteopontin Level in Aged Bone Marrow
2025
Exosome-Mediated RUNX3 DNA Delivery for Lung Cancer Therapy
ACS Appl. Mater. Interfaces 2025 Dec 17(49):66339–66357. doi: 10.1021/acsami.5c15987
Molecular signals associated with intraperitoneal chemotherapy resistance in gastric cancer with peritoneal metastasis
Sci Rep 2025;15(1):35682. doi: 10.1038/s41598-025-19515-4
Synergistic Epigenetic Modulation by 5-Aza-2′-Deoxycytidine and Wnt3a Drives Osteogenic Trans-Differentiation of 3T3-L1 Pre-adipocytes Through Ywhah and Ywhae
Epigenomics 2025;17(14):923-933. doi: 10.1080/17501911.2025.2544513
The dimethyloxalylglycine-functionalized nanofibers for in situ regeneration of infected developing dental roots
Mater Today Bio 2025;33:102062. doi: 10.1016/j.mtbio.2025.102062
Rapid-turnaround mRNA-based personalized cancer vaccines targeting MHC-II neoantigens enhance immunotherapeutic efficacy in colorectal cancer
Adv Sci 2025 Jul:e06426. doi: 10.1002/advs.202506426
Improved bone regeneration with bone targeted scaffold
Sci Rep 2025;15(1):27002. doi: 10.1038/s41598-025-12497-3
Unraveling the Dynamics of Osteoblast Differentiation: Transcriptomic Insights into Matrix Mineralization and Cell Proliferation
BONE 2025 Mar;194:117442. doi: 10.1016/j.bone.2025.117442
Combinational regenerative inductive effect of bio-adhesive hybrid hydrogels conjugated with hiPSC-derived myofibers and its derived EVs for volumetric muscle regeneration
Bioact Mater 2025 Jan;43:579-602. doi: 10.1016/j.bioactmat.2024.09.013
2024
Decorin as a key marker of desmoplastic cancer-associated fibroblasts mediating first-line immune checkpoint blockade resistance in metastatic gastric cancer
Gastric Cancer 2024 Nov 9. doi: 10.1007/s10120-024-01567-6
Engineering Large-Scale hiPSC-derived Vessel-integrated Muscle-like Lattices for Enhanced Volumetric Muscle Regeneration
Trends Biotechnol 2024 Sep. doi: 10.1016/j.tibtech.2024.08.001
Hierarchical Chitin Nanocrystal-Based 3D Printed Dual-Layer Membranes Hydrogels: A Dual Drug Delivery Nano-Platform for Periodontal Tissue Regeneration
ACS Nano 2024 Aug. doi: 10.1021/acsnano.4c05558
Long noncoding RNA MALAT1 mediates fibrous topography-driven pathologic calcification through trans-differentiation of myoblasts
Mater Today Bio 2024;28:101182. doi: 10.1016/j.mtbio.2024.101182
Bone Targeted Lipoplex Loaded 3D Bioprinting Bilayer Scaffold Enhanced Bone Regeneration
Regen Biomater 2024;11:rbae055. doi: 10.1093/rb/rbae055
Deciphering metastatic route-specific signals and their microenvironment interactions in peritoneal metastasis of gastric cancer
Cancer Commun 2024 Mar 1. doi: 10.1002/cac2.12533
Prognostic DNA Mutation and mRNA Expression Analysis of Perineural Invasion in Oral Squamous Cell Carcinoma
Sci Rep 2024 Jan 29. doi: 10.1038/s41598-024-52745-6
2023
MESIA: Multi-Epigenome Sample Integration Approach for Precise Peak Calling
Sci Rep 2023 Nov 27. doi: 10.1038/s41598-023-47948-2
Foci-Xpress: Automated and fast nuclear foci counting tool
Int J Mol Sci 2023 Sep 23. doi: 10.3390/ijms241914465
Peptidylarginine deiminase 2 plays a key role in osteogenesis by enhancing RUNX2 stability through citrullination
Cell Death Dis 2023 Aug 30. doi: 10.1038/s41419-023-06101-7
Nicotinamide enhances osteoblast differentiation through the activation of mitochondrial antioxidant defense system
Exp Mol Med 2023 Jul 18. doi: 10.1038/s12276-023-01041-w
Genomic and evolutionary characteristics of metastatic gastric cancer by routes
Br J Cancer 2023 Jul 08. doi: 10.1038/s41416-023-02338-3
The cumulative survival rate of sandblasted, large-grit, acid-etched dental implants: a retrospective analysis
J Periodontal Implant Sci 2023 Jun. doi: 10.5051/jpis.2301440072
2022
Prognostic Genomic Markers of Pathological Stage in Oral Squamous Cell Carcinoma
Head Neck Pathol 2022 Dec 31. doi: 10.1007/s12105-022-01516-8
Dental implant proximity to adjacent teeth: A retrospective study
Clin Implant Dent Relat Res 2022 Dec;24(6):733-739. doi: 10.1111/cid.13132
Clinico-pathologic and genomic characteristics of mucinous gastric adenocarcinoma
Gastric Cancer 2022;25(4):697-711. doi: 10.1007/s10120-022-01295-9
Nanofibrous topography-driven altered responsiveness to Wnt5a mediates the three-dimensional polarization of odontoblasts
Mater Today Bio 2022 Nov;17:100479. doi: 10.1016/j.mtbio.2022.100479
The worldwide patent landscape of dental implant technology
Biomater Res 2022;26(1):59. doi: 10.1186/s40824-022-00307-0
2021
Septal chondrocyte hypertrophy contributes to midface deformity in a mouse model of Apert syndrome
Sci Rep 2021 Apr;11(1):7979. doi: 10.1038/s41598-021-87260-5
Genetic differences between physical injury patients with and without PTSD by whole-exome sequencing
Clin Psychopharmacol Neurosci 2021;19(4):683-694. doi: 10.9758/cpn.2021.19.4.683
Unveiling the genetic variation of severe continuous/mixed-type ossification of the posterior longitudinal ligament by whole-exome sequencing
Spine J 2021;21(11):1847-1856. doi: 10.1016/j.spinee.2021.07.005
Genetic markers for depressive disorders with earlier age at onset
Prog Neuropsychopharmacol Biol Psychiatry 2021;108:110176. doi: 10.1016/j.pnpbp.2020.110176
Current advances of epigenetics in periodontology from ENCODE project: a review and future perspectives
Clin Epigenetics 2021;13(1):92. doi: 10.1186/s13148-021-01074-w
2020
Intratesticular Peptidyl Prolyl Isomerase 1 Protein Delivery Using Cationic Lipid Coated Fibroin Nanoparticle Complexes Rescues Male Infertility in Mice
ACS Nano 2020 Oct;14(10):13217-13231. doi: 10.1021/acsnano.0c04936
RUNX2-modifying enzymes: therapeutic targets for bone disease
Exp Mol Med 2020 Aug;52(8):1178-1184. doi: 10.1038/s12276-020-0471-4
Sex differences in the genetic architecture of depression
Sci Rep 2020;10(1):9927. doi: 10.1038/s41598-020-66672-9
Genetic markers for later remission in response to early improvement of antidepressants
Int J Mol Sci 2020 Jul;21(14):4884. doi: 10.3390/ijms21144884
Post-Translational Regulations of Transcriptional Activity of RUNX2
Mol Cells 2020;43(2):160-167. doi: 10.14348/molcells.2019.0247
Histone acetylation together with DNA demethylation empowers higher plasticity in adipocytes to differentiate into osteoblasts
Gene 2020 Apr;733:144274. doi: 10.1016/j.gene.2019.144274
Aggregate removal of particulate matter by selective protein-rich fraction of Moringa oleifera extract
J Ind Eng Chem 2020 Jan;81:161-166. doi: 10.1016/j.jiec.2019.09.004
~ 2019
Is NF2 a key player in the differentially expressed gene of spinal cord ependymoma compared with the intracranial ependymoma?
World Neurosurg 2018;118:e906-e917. doi: 10.1016/j.wneu.2018.07.096
Predicting Treatable traits for Long-Acting Bronchodilators in Patients with Stable COPD
Int J COPD 2017;12:3557-3565. doi: 10.2147/COPD.S151909
Fibroin particle-supported cationic lipid layers for highly efficient intracellular protein delivery
Biomaterials 2017 Apr;122:154-162. doi: 10.1016/j.biomaterials.2017.01.019
Direct Delivery of Recombinant Pin1 Protein Rescued Osteoblast Differentiation of Pin1-Deficient Cells
J Cell Physiol 2017 Oct;232(10):2798-2805. doi: 10.1002/jcp.25673
Blood-testis barrier integrity depends on Pin1 expression in Sertoli cells
Sci Rep 2017 Aug;7(1):6977. doi: 10.1038/s41598-017-07229-1
Association of FAT1 mutation with overall survival in patients with HPV-negative head and neck squamous cell carcinoma
Head Neck 2016 Apr;38 Suppl 1:E2021-9. doi: 10.1002/hed.24372
Epigenetic modifications and canonical WNT signaling enable trans-differentiation of nonosteogenic cells into osteoblasts
J Biol Chem 2014 Jul;289(29):20120-8. doi: 10.1074/jbc.M114.558064
Prolyl isomerase Pin1-mediated conformational change and subnuclear focal accumulation of Runx2 are crucial for FGF2-induced osteoblast differentiation
J Biol Chem 2014 Mar;289(13):8828-38. doi: 10.1074/jbc.M113.516237
Wnt3a stimulates Mepe expression directly by canonical Wnt signaling and indirectly through autocrine Bmp-2
J Cell Physiol 2012 Jun;227(6):2287-96. doi: 10.1002/jcp.24038
Frequent clonotypes and its corresponding epitopes in mCD4+ and mCD8+ T-cells
Prediction model of fitness of clonotypes in mCD4+ and mCD8+ T-cells
Comprehensive analysis of shared clonotypes between memory CD4+ and CD8+ T-cells with TCR Repertoire and scRNA sequencing
Analysis pipeline of shared clonotypes between CD4+ and CD8+ T-cells for precision medicine
Composition for diagnostics and the uses comprising SPP1 for immature neutrophil deposition of aging bone marrow
Method for screening biomarkers for diagnosis of ovarian metastatic gastric cancer and biomarkers selected by the method
Method for screening biomarkers for diagnosis of peritoneal metastatic gastric cancer and biomarkers selected by the method
Method for screening biomarkers for predicting prognosis and metastasis of gastric cancer and biomarkers selected by the method
Composition for predicting resistance to anti-PD-1 immune checkpoint inhibitor
Biomarker composition for diagnosing diabetes comprising ITLN1 protein or a gene encoding the same as an active ingredient
* Co-first author · # Corresponding author
For a complete publication list, contact the lab or visit the PIs' Google Scholar profiles.
For a complete publication list, contact the lab or visit the PIs' Google Scholar profiles.